Welcome to BillboardTop100of.com
2010
| 1 | Ke$ha | TiK ToK |
| 2 | Lady Antebellum | Need You Now |
| 3 | Train | Hey, Soul Sister |
| 4 | Katy Perry feat. Snoop Dogg | California Gurls |
| 5 | Usher feat. will.i.am | OMG |
| 6 | B.o.B feat. Hayley Williams | Airplanes |
| 7 | Eminem feat. Rihanna | Love The Way You Lie |
| 8 | Lady Gaga | Bad Romance |
| 9 | Taio Cruz | Dynamite |
| 10 | Taio Cruz feat. Ludacris | Break Your Heart |
| 11 | B.o.B feat. Bruno Mars | Nothin’ On You |
| 12 | Enrique Iglesias feat. Pitbull | I Like It |
| 13 | Young Money feat. Lloyd | Bedrock |
| 14 | Jason Derulo | In My Head |
| 15 | Rihanna | Rude Boy |
| 16 | Lady Gaga feat. Beyonce | Telephone |
| 17 | Katy Perry | Teenage Dream |
| 18 | Bruno Mars | Just The Way You Are |
| 19 | Mike Posner | Cooler Than Me |
| 20 | Black Eyed Peas | Imma Be |
| 21 | Jay-Z and Alicia Keys | Empire State of Mind |
| 22 | Usher feat. Pitbull | DJ Got Us Fallin’ in Love |
| 23 | Travie McCoy feat. Bruno Mars | Billionaire |
| 24 | Eminem | Not Afraid |
| 25 | Iyaz | Replay |
| 26 | David Guetta feat. Akon | Sexy Chick |
| 27 | The Script | Breakeven |
| 28 | Ke$ha | Your Love Is My Drug |
| 29 | Black Eyed Peas | I Gotta Feeling |
| 30 | Owl City | Fireflies |
| 31 | Trey Songz feat. Fabolous | Say Aah |
| 32 | Drake | Find Your Love |
| 33 | Lady Gaga | Alejandro |
| 34 | Jason Derulo | Ridin’ Solo |
| 35 | Nelly | Just A Dream |
| 36 | Ludacris | How Low |
| 37 | Far East Movement feat. The Cataracs and Dev | Like A G6 |
| 38 | Timbaland feat. Justin Timberlake | Carry Out |
| 39 | Michael Buble | Haven’t Met You Yet |
| 40 | Flo Rida feat. David Guetta | Club Can’t Handle Me |
| 41 | Jay Sean feat. Lil Wayne | Down |
| 42 | La Roux | Bulletproof |
| 43 | Jason Derulo | Whatcha Say |
| 44 | Justin Bieber feat. Ludacris | Baby |
| 45 | Adam Lambert | Whataya Want From Me |
| 46 | Taylor Swift | Mine |
| 47 | Rihanna | Only Girl (In The World) |
| 48 | Kris Allen | Live Like We’re Dying |
| 49 | Rihanna feat. Jeezy | Hard |
| 50 | Jay-Z and Mr. Hudson | Young Forever |
| 51 | Ke$ha feat. 3OH!3 | Blah Blah Blah |
| 52 | Trey Songz feat. Nicki Minaj | Bottoms Up |
| 53 | Jay Sean feat. Sean Paul & Lil Jon | Do You Remember |
| 54 | OneRepublic | All The Right Moves |
| 55 | Orianthi | According To You |
| 56 | Ludacris feat. Nicki Minaj | My Chick Bad |
| 57 | Taylor Swift | You Belong With Me |
| 58 | Black Eyed Peas | Meet Me Halfway |
| 59 | Ke$ha | Take It Off |
| 60 | Drake | Over |
| 61 | Neon Trees | Animal |
| 62 | Maroon 5 | Misery |
| 63 | B.o.B feat. Rivers Cuomo | Magic |
| 64 | Lady Gaga | Paparazzi |
| 65 | New Boyz feat. Ray J | Tie Me Down |
| 66 | Nicki Minaj | Your Love |
| 67 | Miley Cyrus | Party In The U.S.A. |
| 68 | Chris Brown feat. Tyga and Kevin McCall | Deuces |
| 69 | Britney Spears | 3 |
| 70 | Shontelle | Impossible |
| 71 | Drake feat. Kanye West, Lil Wayne and Eminem | Forever |
| 72 | Boys Like Girls feat. Taylor Swift | Two Is Better Than One |
| 73 | 3OH!3 feat. Ke$ha | My First Kiss |
| 74 | Kelly Clarkson | Already Gone |
| 75 | Black Eyed Peas | Rock That Body |
| 76 | OneRepublic | Secrets |
| 77 | Selena Gomez and The Scene | Naturally |
| 78 | Alicia Keyes | Un-Thinkable (I’m Ready) |
| 79 | DJ Khaled feat. T-Pain, Ludacris, Snoop Dogg and Rick Ross | All I Do Is Win |
| 80 | Kevin Rudolf feat. Birdman, Jay Sean, & Lil Wayne | I Made It (Cash Money Heroes) |
| 81 | Sugarland | Stuck Like Glue |
| 82 | Usher feat. Plies | Hey Daddy (Daddy’s Home) |
| 83 | Usher | There Goes My Baby |
| 84 | Taylor Swift | Today Was A Fairytale |
| 85 | Timbaland feat. Drake | Say Something |
| 86 | Beyonce | Sweet Dreams |
| 87 | Kings of Leon | Use Somebody |
| 88 | Carrie Underwood | Undo It |
| 89 | Sean Kingston and Justin Bieber | Eenie Meenie |
| 90 | Lil Wayne feat. Drake | Right Above It |
| 91 | Miranda Lambert | The House That Built Me |
| 92 | The Band Perry | If I Die Young |
| 93 | Paramore | The Only Exception |
| 94 | Lady Antebellum | American Honey |
| 95 | Sara Bareilles | King Of Anything |
| 96 | Daughtry | Life After You |
| 97 | Uncle Kraker | Smile |
| 98 | Cali Swag District | Teach Me How To Dougie |
| 99 | Alicia Keyes | Try Sleeping With A Broken Heart |
| 100 | Jerrod Niemann | Lover, Lover |